Preprints
Multiplexed Gene Synthesis in Emulsions for Exploring Protein Functional Landscapes
Calin Plesa, Angus M. Sidore, Nathan Lubock, Di Zhang, Sriram Kosuri
bioRxiv 163550; doi: https://doi.org/10.1101/163550
Highly parallel genome variant engineering with CRISPR/Cas9 in eukaryotic cells
Meru J. Sadhu, Joshua S. Bloom, Laura Day, Jake J. Siegel, Sriram Kosuri, Leonid Kruglyak
bioRxiv 147637; doi: https://doi.org/10.1101/147637
A systematic comparison of error correction enzymes by next-generation sequencing
Nathan B Lubock, Di Zhang, George M Church, Sriram Kosuri
bioRxiv 100685; doi: https://doi.org/10.1101/100685
Multiplexed Gene Synthesis in Emulsions for Exploring Protein Functional Landscapes
Calin Plesa, Angus M. Sidore, Nathan Lubock, Di Zhang, Sriram Kosuri
bioRxiv 163550; doi: https://doi.org/10.1101/163550
Highly parallel genome variant engineering with CRISPR/Cas9 in eukaryotic cells
Meru J. Sadhu, Joshua S. Bloom, Laura Day, Jake J. Siegel, Sriram Kosuri, Leonid Kruglyak
bioRxiv 147637; doi: https://doi.org/10.1101/147637
A systematic comparison of error correction enzymes by next-generation sequencing
Nathan B Lubock, Di Zhang, George M Church, Sriram Kosuri
bioRxiv 100685; doi: https://doi.org/10.1101/100685
Published
Genetic Engineering: Lassoing Genomic Libraries (Perspective)
Nathan B. Lubock & Sriram Kosuri
Nature Biomedical Engineering, (2017) doi:10.1038/s41551-017-0098
Engineering an allosteric transcription factor to respond to new ligands
Noah D Taylor, Alexander S Garruss, Rocco Moretti, Sum Chan, Mark A Arbing, Duilio Cascio, Jameson K Rogers, Farren J Isaacs, Sriram Kosuri, David Baker, Stanley Fields, George M Church and Srivatsan Raman
Nature Methods, (2016) doi:10.1038/nmeth.3696
Direct Mutagenesis of Thousands of Genomic Targets Using Microarray-Derived Oligonucleotides
Mads T Bonde*, Sriram Kosuri*, Hans J Genee, Kira Sarup-Lytzen, George M Church, Morten OA Sommer, and Harris H Wang
ACS Synthetic Biology, (2014) doi:10.1021/sb5001565
Large-scale de novo DNA synthesis: technologies and applications (Review)
Sriram Kosuri and George M Church
Nature Methods, (2014) doi:10.1038/nmeth.2918
Causes and effects of N-terminal codon bias in bacterial genes
Daniel B Goodman, George M Church, Sriram Kosuri
Science, (2013) doi:10.1126/science.1241934
Probing the Limits of Genetic Recoding in Essential Genes
Marc Lajoie*, Sriram Kosuri*, Joshua Mosberg, Christopher Gregg, Di Zhang, George M Church
Science, (2013) doi:10.1126/science.1241460
Composability of regulatory sequences controlling transcription and translation in E. coli
Sriram Kosuri*, Daniel B Goodman*, Guillaume Cambray, Vivek K Mutalik, Yuan Gao, Adam P. Arkin, Drew Endy, George M Church
PNAS, (2013) doi:10.1073/pnas.1301301110
CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
Prashant Mali, John Aach, P Benjamin Stranges, Kevin M Esvelt, Mark Moosburner, Sriram Kosuri, Luhan Yang, George M Church
Nature Biotechnology, (2013) doi:10.1038/nbt.2675
Next-Generation Digital Information Storage in DNA
George M. Church, Yuan Gao, Sriram Kosuri
Science (2012) doi:10.1126/science.1226355
When It Rains, It Pores (Perspective)
Sriram Kosuri & A. Michael Sismour
ACS Synthetic Biology (2012) doi:10.1021/sb300015f
Gene Assembly from Chip-Synthesized Oligonucleotides
Nikolai Eroshenko*, Sriram Kosuri*, Adam H Marblestone, Nicholas Conway, & George Church
Current Protocols in Chemical Biology (2012) doi:10.1002/9780470559277.ch110190
Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription
Feng Zhang*, Le Cong*, Simona Lodato, Sriram Kosuri, George Church & Paola Arlotta
Nature Biotechnology (2011) doi:10.1038/nbt.1775
Scalable gene synthesis by selective amplification of DNA pools from high-fidelity microchips
Sriram Kosuri*, Nikolai Eroshenko*, Emily LeProust, Michael Super, Jeffrey Way, Jin Billy Li & George Church
Nature Biotechnology (2010) 28:1295 doi:10.1038/nbt.1716
TABASCO: A single molecule, base-pair resolved gene expression simulator
Sriram Kosuri, Jason Kelly, & Drew Endy
BMC Bioinformatics 2007, 8:480 doi:10.1186/1471-2105-8-480
Refactoring bacteriophage T7
Leon Y. Chan*, Sriram Kosuri* & Drew Endy
Molecular Systems Biology 13 September 2005 doi:10.1038/msb4100025
Genetic Engineering: Lassoing Genomic Libraries (Perspective)
Nathan B. Lubock & Sriram Kosuri
Nature Biomedical Engineering, (2017) doi:10.1038/s41551-017-0098
Engineering an allosteric transcription factor to respond to new ligands
Noah D Taylor, Alexander S Garruss, Rocco Moretti, Sum Chan, Mark A Arbing, Duilio Cascio, Jameson K Rogers, Farren J Isaacs, Sriram Kosuri, David Baker, Stanley Fields, George M Church and Srivatsan Raman
Nature Methods, (2016) doi:10.1038/nmeth.3696
Direct Mutagenesis of Thousands of Genomic Targets Using Microarray-Derived Oligonucleotides
Mads T Bonde*, Sriram Kosuri*, Hans J Genee, Kira Sarup-Lytzen, George M Church, Morten OA Sommer, and Harris H Wang
ACS Synthetic Biology, (2014) doi:10.1021/sb5001565
Large-scale de novo DNA synthesis: technologies and applications (Review)
Sriram Kosuri and George M Church
Nature Methods, (2014) doi:10.1038/nmeth.2918
Causes and effects of N-terminal codon bias in bacterial genes
Daniel B Goodman, George M Church, Sriram Kosuri
Science, (2013) doi:10.1126/science.1241934
Probing the Limits of Genetic Recoding in Essential Genes
Marc Lajoie*, Sriram Kosuri*, Joshua Mosberg, Christopher Gregg, Di Zhang, George M Church
Science, (2013) doi:10.1126/science.1241460
Composability of regulatory sequences controlling transcription and translation in E. coli
Sriram Kosuri*, Daniel B Goodman*, Guillaume Cambray, Vivek K Mutalik, Yuan Gao, Adam P. Arkin, Drew Endy, George M Church
PNAS, (2013) doi:10.1073/pnas.1301301110
CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
Prashant Mali, John Aach, P Benjamin Stranges, Kevin M Esvelt, Mark Moosburner, Sriram Kosuri, Luhan Yang, George M Church
Nature Biotechnology, (2013) doi:10.1038/nbt.2675
Next-Generation Digital Information Storage in DNA
George M. Church, Yuan Gao, Sriram Kosuri
Science (2012) doi:10.1126/science.1226355
When It Rains, It Pores (Perspective)
Sriram Kosuri & A. Michael Sismour
ACS Synthetic Biology (2012) doi:10.1021/sb300015f
Gene Assembly from Chip-Synthesized Oligonucleotides
Nikolai Eroshenko*, Sriram Kosuri*, Adam H Marblestone, Nicholas Conway, & George Church
Current Protocols in Chemical Biology (2012) doi:10.1002/9780470559277.ch110190
Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription
Feng Zhang*, Le Cong*, Simona Lodato, Sriram Kosuri, George Church & Paola Arlotta
Nature Biotechnology (2011) doi:10.1038/nbt.1775
Scalable gene synthesis by selective amplification of DNA pools from high-fidelity microchips
Sriram Kosuri*, Nikolai Eroshenko*, Emily LeProust, Michael Super, Jeffrey Way, Jin Billy Li & George Church
Nature Biotechnology (2010) 28:1295 doi:10.1038/nbt.1716
TABASCO: A single molecule, base-pair resolved gene expression simulator
Sriram Kosuri, Jason Kelly, & Drew Endy
BMC Bioinformatics 2007, 8:480 doi:10.1186/1471-2105-8-480
Refactoring bacteriophage T7
Leon Y. Chan*, Sriram Kosuri* & Drew Endy
Molecular Systems Biology 13 September 2005 doi:10.1038/msb4100025
